Fondation Jean Dausset – CEPH (Paris) is involved in large research projects (in particular the LABEX GENMED, in order to study causes of complex diseases using high throughput technologies generating large volumes of data
Job description:
to reinforce the bioinformatics team in Fondation Jean DAUSSET - CEPH, a permanent position is opened.
The recruited person will participate into the data analyses (NGS) of different ongoing projects (cancers, longevity in particular) and will be asked to:
● set up pipelines and in particular: - selecting / testing new bioinformatic tools - do scientific monitoring
● create original analysis tools based on genomics data for publication purpose
● do the analyses / interpretation of results for publication purpose
Compte tenu du lancement du programme national France Médecine Génomique 2025 coordonnée par l'alliance AVIESAN et des besoins grandissant en matière de formation à la génomique humaine et médicale, Genopole et ses partenaires institutionnels organisent une école d'été de haut niveau en bioinformatique et biostatistiques pour la génomique à visée médicale.
Fondation Jean Dausset – CEPH (Paris) is involved in large research projects (in particular the LABEX GENMED, in order to study causes of complex diseases using high throughput technologies generating large volumes of data
Job description: immunotherapies came to light in recent years with different successes of treatments against cancer (anti-PD1 et anti-CTLA4 for some forms of melanomas and lung cancers, anti-PD1 against some forms of metastatic colorectal cancers in particular). These different successes are however counter-balanced with a relatively high percentage of non responding treated patients indicating that a more refined stratification for patients to treat could be beneficial for non responding patients. In order to do so, different features associated to treatment response have been reported in the litterature (mutational load, neoepitopic load, the degree of aneuploïdy, etc.). The combination of these different features seems to better predict the response treatment than one feature taken alone. In order to improve the stratification of these patients, we are developing a tool integrating all these different components in order to propose a more refined stratification of patients eligible for immunotherapies. We are thus proposing, in this context, a 2 year GENMED postdoctoral position to contribute to the development of this tool for publication purpose. The recruited person will also participate into the analysis / interpretation of results of ongoing projects for publication purpose.
Mardi 13 septembre 2016, la grande majorité des internes de génétique médicale de toute la France (65 médecins) ont assisté à une journée d’information organisée par le Labex GENMED dont une des missions centrales est de promouvoir la formation en génomique médicale.